The interaction of MHC and TCR generates a T cell-mediated immune response, and MHC-associated molecules present the peptide to antigen-specific T cells that recognize the peptide. Creative BioMart can customize any routine immunological T cell function assay, enabling researchers to quickly assess the regulation of T cell function by novel targets with our series of T cell assay services to meet your needs.

What MHC Molecules Can Do

Use MHC molecules to discover antigen-specific T cells as well as to assess T cell-specific functions. Our MHC-related products provide increased assay specificity and flexibility and can be pre-loaded with peptides associated with certain diseases to assemble into complexes for flow cytometry detection of T cells based on their unique receptors.

Our T Cell Function Test Services

• T Cell Activation and Cytokine Response Assay
  It is important to analyze the T cell reactivity involved in MHC, and we offer cytokine assays for T cell analysis. Our cytokine response testing service is designed to help researchers evaluate pMHC complexes or candidate epitopes through a comprehensive analysis of TCR engagement pathways.
• T Cell Proliferation Assay
  We are committed to providing a comprehensive range of MHC products and available testing services for T-cell function and immunological knowledge development. Our custom MHC peptide-related complexes are available for T cell analysis and T cell proliferation assays can be used to assess T cell viability after stimulation with specific antigenic epitopes.
• T Cell Exhaustion Assay
  The T cell exhaustion assay service is designed to help researchers test the long-term effects of epitopes of interest on T cell function. We will design a personalized and comprehensive test protocol for your study, and you can select our MHC-related molecules for T-cell stimulation to help you analyze whether the epitope of interest causes T-cell decay.
• T Cell Chemotaxis Assay
  T-cell chemotaxis assessment services help researchers evaluate T-cell migration levels following specific antigen stimulation, including 2D and 3D chemotaxis assays, in combination with other indicator instruments to assess T-cell function. We offer customization of pMHC complexes to help test the effect of molecules of interest on T cell chemotaxis.
• T Cell-Associated Cytotoxicity Assay
  Our services are designed to help clients test the function of molecules of interest by providing them with a variety of methods for measuring CD8⁺ T cell toxicity, including in vitro and in vivo assays that primarily analyze T cell activity. Our platform offers a full range of MHC reagents suitable for T-cell analysis and provides you with high quality analytical results.

Our Advantages

• Standardized T-cell assays
• A range of custom reagents suitable for the assay
• T-cell assays for multiple targets
• Comprehensive and validated testing

Creative BioMart provides researchers with T-cell function testing services to quickly assess the regulation of T-cell function by various novel therapies with our range of T-cell assays. We offer optimized and customizable pMHC complex reagents for T-cell assays, setting you on the path to discovery for your cell therapy, gene therapy or small molecule drug.

Enhance your drug discovery program by leveraging our extensive T-cell assays with our expert panelists who are here to provide the guidance and services you need, contact us today!