Products

PE-Labeled Human Peptide Ready HLA-A*02:01&B2M Tetramer

Overview Specification

Product Name	PE-Labeled Human Peptide Ready HLA-A*02:01&B2M Tetramer
Cat. No.	MHCRP-0665
Category	Proteins & Peptides
Product Description	Recombinant PE-Labeled Human Peptide Ready HLA-A02:01&B2M Tetramer is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human Peptide Ready HLA-A02:01&B2M Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305 (HLA-A*02:01) and Ile21-Met119 (B2M).
Size	100/500 μg
Format	Liquid. Supplied as 0.22 μm filtered solution in PBS, 100 mM L-arginine, 0.2% BSA (pH 7.4).
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	A0A140T913(HLA-A*02:01)&P61769(B2M)
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Tetramer
Gene Synonyms	MHC; HLA-A*02:01; Peptide Ready
Amino Acid Range	Gly25-Thr305 (HLA-A*02:01) & Ile21-Met119 (B2M)
Activity	Immobilized PE-labeled human peptide ready HLA-A*02:01&B2M tetramer, His tag at 0.5 μg/mL (100 μL/well) on the plate. Dose response curve for anti-HLA class I (W6/32) antibody, hFc tag with the EC50 of 4.4 ng/mL determined by ELISA.
Product Background	Peptide Ready HLA-A02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
Allele	HLA-A*02:01
Biotinylated	No

For research or industrial raw materials, not for personal medical use!