Products

PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 Tetramer, HEK293

Overview Specification

Product Name	PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 Tetramer, HEK293
Cat. No.	MHCRP-0641
Category	Proteins & Peptides
Product Description	Recombinant PE-Labeled Human HLA-A02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and GVYDGREHTV peptide.
Size	100/500 μg
Format	Liquid. Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	A0A140T913(HLA-A*02:01)&P61769(B2M)&GVYDGREHTV
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Tetramer
Gene Synonyms	HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4
Amino Acid Range	Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M), and GVYDGREHTV peptide
Activity	Immobilized anti-HLA-A02:01&B2M&MAGE-A4 (GVYDGREHTV) antibody, hFc tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for PE labeled human HLA-A02:01&B2M&MAGE-A4 (GVYDGREHTV) tetramer, His tag with the EC50 of 0.21 μg/mL determined by ELISA.
Product Background	Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene. The MAGE-A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A0201 MAGE-A4 (GVYDGREHTV) complex Protein is a complex of HLA-A0201 of -the MHC Class I, B2M and GVYDGREHTV peptide of -the MAGE-A4.
Allele	HLA-A*02:01
Biotinylated	No

For research or industrial raw materials, not for personal medical use!