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| Product Name | PE-Labeled Human HLA-A*02:01&B2M&CMV pp65 Tetramer |
| Cat. No. | MHCRP-0637 |
| Category | Proteins & Peptides |
| Product Description | Recombinant PE-Labeled Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and NLVPMVATV peptide. |
| Size | 100/500 μg |
| Format | Liquid. Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4). |
| Storage | Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping Temp | Shipped at ambient temperature. |
| Lead Time | Product delivery time depends on the supplier. |
| Species | Human |
| Expression Host | HEK293 |
| Accession No | A0A140T913(HLA-A*02:01)&P61769(B2M)&NLVPMVATV |
| Tag | C-His-Avi |
| Tag Position | C-terminus |
| Molecular Type | Tetramer |
| Gene Synonyms | MHC; HLA-A*02:01; CMV pp65 |
| Amino Acid Range | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M), and NLVPMVATV peptide |
| Fluorophore | PE |
| Product Background | Human cytomegalovirus (CMV) is one of the major causes of severe complications in immunocompromised patients, such as recipients of hematopoietic cells, solid organ transplantation, and HIV-infected individuals. CMV is also a major pathogen in congenital infection. It can cause life-threatening diseases and severe neurological sequelae in newborn infants. CMV phosphoprotein pp65 is thought to be a major antigen for CMV-specific cellular immunity. |
| Allele | HLA-A*02:01 |
| Biotinylated | No |
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