Products

Mouse Qa-1b&B2M&Qdm Monomer

Overview Specification

Product Name	Mouse Qa-1b&B2M&Qdm Monomer
Cat. No.	MHCRP-0635
Category	Proteins & Peptides
Product Description	Recombinant Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus; It contains His23-Pro296(Qa-1b), Ile21-Met119 (B2M) and AMAPRTLLL peptide.
Size	100/500 μg
Format	Lyophilized from 0.22 μm filtered solution in PBS, 100 mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Mouse
Expression Host	HEK293
Accession No	P06339(Q1-1b)&P01887(B2M)&AMAPRTLLL
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Gene Synonyms	Qdm; Qa-1b; MHC; H2-T23
Endotoxin Residue	Less than 1 EU per μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	His23-Pro296(Qa-1b), Ile21-Met119 (B2M), and AMAPRTLLL peptide
Product Background	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
Allele	Qa-1b
Biotinylated	No

For research or industrial raw materials, not for personal medical use!