Products

Human HLA-A*24:02&B2M&MAGE-A3 Monomer

Overview Specification

Product Name	Human HLA-A*24:02&B2M&MAGE-A3 Monomer
Cat. No.	MHCRP-0613
Category	Proteins & Peptides
Product Description	Recombinant Human MAGE-A3 (HLA-A24:02) Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305 (HLA-A24:02), Ile21-Met119 (B2M) and IMPKAGLLI peptide.
Size	100/500 μg
Format	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	AAA59600.1(HLA-A*24:02)&P61769(B2M)&IMPKAGLLI
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 50.20 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Gene Synonyms	Melanoma-associated antigen 3; MZ2-D; MZ2D; MZ2-D; CT1.3; MAGE-3
Endotoxin Residue	Less than 1 EU per μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	Gly25-Thr305 (HLA-A*24:02), Ile21-Met119 (B2M), and IMPKAGLLI peptide
Product Background	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCA.
Allele	HLA-A*24:02
Biotinylated	No

For research or industrial raw materials, not for personal medical use!