Products

Human HLA-A*02:01&B2M&MTMR5 Monomer

Overview Specification

Product Name	Human HLA-A*02:01&B2M&MTMR5 Monomer
Cat. No.	MHCRP-0523
Category	Proteins & Peptides
Product Description	Recombinant Human HLA-A02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein is expressed from E. coli* with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KMQGAPPAV peptide.
Size	100/500 μg
Format	Liquid. Supplied as 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl (pH 8.0).
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped with dry ice.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	E. coli
Accession No	A0A140T913(HLA-A*02:01)&P61769(B2M)&KMQGAPPAV
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Gene Synonyms	KMQGAPPAV; MTMR5
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M), and KMQGAPPAV peptide
Activity	Immobilized human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) monomer, His tag at 0.5 μg/mL (100 μL/well) on the plate. Dose response curve for anti-B2M antibody, mFc tag with the EC50 of 9.0 ng/mL determined by ELISA (QC Test).
Product Background	The human SBF1 (SET binding factor 1) gene, alternatively known as MTMR5, is predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset neurocognitive disorders (NCDs), such as Alzheimer's disease.
Allele	HLA-A*02:01
Biotinylated	No

For research or industrial raw materials, not for personal medical use!