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| Product Name | Human HLA-A*01:01&B2M&CT83 Tetramer |
| Cat. No. | MHCRP-0472 |
| Category | Proteins & Peptides |
| Product Description | Recombinant Human CT83 (HLA-A*01:01) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus, tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305 (HLA-A*01:01), Ile21-Met119 (B2M) and NTDNNLAVY peptide. |
| Size | 100/500 μg |
| Format | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage | Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping Temp | Shipped with dry ice. |
| Lead Time | Product delivery time depends on the supplier. |
| Species | Human |
| Expression Host | HEK293 |
| Accession No | Q5SUL5(HLA-A*01:01)&P61769(B2M)&NTDNNLAVY |
| Tag | C-His-Avi |
| Tag Position | C-terminus |
| Molecular Type | Tetramer |
| Molecular Weight (MV) | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result. |
| Gene Synonyms | CT83; HLA class I; MHC class I; HLA-A; HLA-A*0101; MHC; MHC HLA-A alpha |
| Endotoxin Residue | Less than 1 EU per μg by the LAL method. |
| Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC. |
| Amino Acid Range | Gly25-Thr305 (HLA-A*01:01), Ile21-Met119 (B2M), and NTDNNLAVY peptide |
| Product Background | Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy. |
| Allele | HLA-A*01:01 |
| Biotinylated | No |
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