Products

Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 Monomer

Overview Specification

Product Name	Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 Monomer
Cat. No.	MHCRP-0434
Category	Proteins & Peptides
Product Description	Recombinant Biotinylated Human HLA-E01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer Protein is expressed from HEK293 with His tag and Avi at the C-terminus. It contains Gly22-Thr302 (HLA-E01:03), Ile21-Met119 (B2M) and GGDPHLPTL peptide.
Size	100/500 μg
Format	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	P13747(HLA-E*01:03)&P61769(B2M)&GGDPHLPTL
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 50.15 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.
Gene Synonyms	EBV LMP1; GGDPHLPTL
Endotoxin Residue	Less than 1 EU per μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	Gly22-Thr302 (HLA-E*01:03), Ile21-Met119 (B2M), and GGDPHLPTL peptide
Product Background	Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is expressed in germinal-center-derived, mononuclear Hodgkin (H) and multinuclear, diagnostic Reed-Sternberg (RS) cells in classical EBV-positive Hodgkin's lymphoma (cHL). LMP1 expression in EBV-negative H-cell lines results in a significantly increased number of RS cells.
Allele	HLA-E*01:03
Biotinylated	Yes

For research or industrial raw materials, not for personal medical use!