Products

Biotinylated Human HLA-C*08:01&B2M&KRAS G12D Monomer

Overview Specification

Product Name	Biotinylated Human HLA-C*08:01&B2M&KRAS G12D Monomer
Cat. No.	MHCRP-0433
Category	Proteins & Peptides
Product Description	Recombinant Biotinylated Human HLA-C08:01&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Cys25-Ala366 (HLA-C08:01), Ile21-Met119 (B2M) and GADGVGKSAL peptide.
Size	100/500 μg
Format	Liquid. Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	AAA59688.1(HLA-C*08:01)&P61769(B2M)&GADGVGKSAL
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Gene Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
Endotoxin Residue	Less than 1 EU per μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	Cys25-Ala366 (HLA-C*08:01), Ile21-Met119 (B2M), and GADGVGKSAL peptide
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
Allele	HLA-C*08:01
Biotinylated	Yes

For research or industrial raw materials, not for personal medical use!