Products

Biotinylated Human HLA-A*11:01&B2M&HPV16 E7 Monomer

Overview Specification

Product Name	Biotinylated Human HLA-A*11:01&B2M&HPV16 E7 Monomer
Cat. No.	MHCRP-0403
Category	Proteins & Peptides
Product Description	Recombinant Biotinylated Human HLA-A11:01&B2M&HPV16 E7 (IVCPICSQK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305 (HLA-A11:01), Ile21-Met119 (B2M) and IVCPICSQK peptide.
Size	100/500 μg
Format	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	HEK293
Accession No	AAV53343.1(HLA-A*11:01)&P61769(B2M)&IVCPICSQK
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Monomer
Molecular Weight (MV)	The protein has a predicted MW of 50.39 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Gene Synonyms	HPV16; E7; MHC
Endotoxin Residue	Less than 1 EU per μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC.
Amino Acid Range	Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M), and IVCPICSQK peptide
Product Background	HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
Allele	HLA-A*11:01
Biotinylated	Yes

For research or industrial raw materials, not for personal medical use!