Products

APC-Labeled Human HLA-A*02:01&B2M&CG1 Tetramer

Overview Specification

Product Name	APC-Labeled Human HLA-A*02:01&B2M&CG1 Tetramer
Cat. No.	MHCRP-0328
Category	Proteins & Peptides
Product Description	Recombinant APC-Labeled Human HLA-A02:01&B2M&CG1 (FLLPTGAEA) Tetramer Protein is expressed from E. coli* with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-A02:01&B2M&CG1 (FLLPTGAEA) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin. It contains Gly25-Thr305 (HLA-A02:01), Ile21-Met119 (B2M) and FLLPTGAEA peptide.
Size	100/500 μg
Format	Liquid. Supplied as 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl, 0.2% BSA (pH 8.0).
Storage	Store at -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping Temp	Shipped at ambient temperature.
Lead Time	Product delivery time depends on the supplier.
Species	Human
Expression Host	E. coli
Accession No	A0A140T913(HLA-A*02:01)&P61769(B2M)&FLLPTGAEA
Tag	C-His-Avi
Tag Position	C-terminus
Molecular Type	Tetramer
Gene Synonyms	CG1 (FLLPTGAEA)
Amino Acid Range	Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M), and FLLPTGAEA peptide
Fluorophore	APC
Product Background	Cathepsin G (CG) is a myeloid azurophil granule protease that is highly expressed by acute myeloid leukemia (AML) blasts and leukemia stem cells. CG1 (FLLPTGAEA) is a human leukocyte antigen-A2-restricted nonameric peptide derived from CG that can act as an immunogenic target in AML.
Allele	HLA-A*02:01
Biotinylated	No

For research or industrial raw materials, not for personal medical use!